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  1. Content type: Data Note

    Schistocephalus solidus is a well-established model organism for studying the complex life cycle of cestodes and the mechanisms underlying host-parasite interactions. However, very few...

    Authors: François Olivier Hébert, Stephan Grambauer, Iain Barber, Christian R. Landry and Nadia Aubin-Horth

    Citation: GigaScience 2016 5:24

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  2. Content type: Data Note

    The scabies mite, Sarcoptes scabiei, is a parasitic arachnid and cause of the infectious skin disease scabies in humans and mange in other animal species. Scabies infections are a major health problem, particular...

    Authors: Ehtesham Mofiz, Deborah C. Holt, Torsten Seemann, Bart J. Currie, Katja Fischer and Anthony T. Papenfuss

    Citation: GigaScience 2016 5:23

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  3. Content type: Data Note

    Microbial inhabitants of soils are important to ecosystem and planetary functions, yet there are large gaps in our knowledge of their diversity and ecology. The ‘Biomes of Australian Soil Environments’ (BASE) ...

    Authors: Andrew Bissett, Anna Fitzgerald, Thys Meintjes, Pauline M. Mele, Frank Reith, Paul G. Dennis, Martin F. Breed, Belinda Brown, Mark V. Brown, Joel Brugger, Margaret Byrne, Stefan Caddy-Retalic, Bernie Carmody, David J. Coates, Carolina Correa, Belinda C. Ferrari…

    Citation: GigaScience 2016 5:21

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  4. Content type: COMMENTARY

    Life science research increasingly relies on large-scale computational analyses. However, the code and data used for these analyses are often lacking in publications. To maximize scientific impact, reproducibi...

    Authors: Melissa Gymrek and Yossi Farjoun

    Citation: GigaScience 2016 5:22

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  5. Content type: Data Note

    There are five major extant groups of Echinodermata: Crinoidea (feather stars and sea lillies), Ophiuroidea (brittle stars and basket stars), Asteroidea (sea stars), Echinoidea (sea urchins, sea biscuits, and ...

    Authors: Kyle A. Long, Carlos W. Nossa, Mary A. Sewell, Nicholas H. Putnam and Joseph F. Ryan

    Citation: GigaScience 2016 5:20

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  6. Content type: Commentary

    Ray-finned fishes (Actinopterygii) represent more than 50 % of extant vertebrates and are of great evolutionary, ecologic and economic significance, but they are relatively underrepresented in ‘omics studies. ...

    Authors: Ying Sun, Yu Huang, Xiaofeng Li, Carole C. Baldwin, Zhuocheng Zhou, Zhixiang Yan, Keith A. Crandall, Yong Zhang, Xiaomeng Zhao, Min Wang, Alex Wong, Chao Fang, Xinhui Zhang, Hai Huang, Jose V. Lopez, Kirk Kilfoyle…

    Citation: GigaScience 2016 5:18

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  7. Content type: Research

    The venom of predatory marine cone snails mainly contains a diverse array of unique bioactive peptides commonly referred to as conopeptides or conotoxins. These peptides have proven to be valuable pharmacologi...

    Authors: Chao Peng, Ge Yao, Bing-Miao Gao, Chong-Xu Fan, Chao Bian, Jintu Wang, Ying Cao, Bo Wen, Yabing Zhu, Zhiqiang Ruan, Xiaofei Zhao, Xinxin You, Jie Bai, Jia Li, Zhilong Lin, Shijie Zou…

    Citation: GigaScience 2016 5:17

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  8. Content type: Review

    Brainhack events offer a novel workshop format with participant-generated content that caters to the rapidly growing open neuroscience community. Including components from hackathons and unconferences, as well...

    Authors: R. Cameron Craddock, Daniel S. Margulies, Pierre Bellec, B. Nolan Nichols, Sarael Alcauter, Fernando A. Barrios, Yves Burnod, Christopher J. Cannistraci, Julien Cohen-Adad, Benjamin De Leener, Sebastien Dery, Jonathan Downar, Katharine Dunlop, Alexandre R. Franco, Caroline Seligman Froehlich, Andrew J. Gerber…

    Citation: GigaScience 2016 5:16

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  9. Content type: Review

    ‘Mitochondrial metagenomics’ (MMG) is a methodology for shotgun sequencing of total DNA from specimen mixtures and subsequent bioinformatic extraction of mitochondrial sequences. The approach can be applied to...

    Authors: Alex Crampton-Platt, Douglas W. Yu, Xin Zhou and Alfried P. Vogler

    Citation: GigaScience 2016 5:15

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  10. Content type: Commentary

    Systems biology promises to revolutionize medicine, yet human wellbeing is also inherently linked to healthy societies and environments (sustainability). The IDEA Consortium is a systems ecology open science i...

    Authors: Neil Davies, Dawn Field, David Gavaghan, Sally J. Holbrook, Serge Planes, Matthias Troyer, Michael Bonsall, Joachim Claudet, George Roderick, Russell J. Schmitt, Linda Amaral Zettler, Véronique Berteaux, Hervé C. Bossin, Charlotte Cabasse, Antoine Collin, John Deck…

    Citation: GigaScience 2016 5:14

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  11. Content type: Data Note

    We investigated whether images obtained through X-ray micro-computed tomography (μCT) can be used in conjunction with traditional methods for morphological studies of soft-bodied land planarians. μCT is non-in...

    Authors: Fernando Carbayo and Jennifer Winifred Lenihan

    Citation: GigaScience 2016 5:13

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  12. Content type: Technical Note

    Metabolomics is increasingly recognized as an invaluable tool in the biological, medical and environmental sciences yet lags behind the methodological maturity of other omics fields. To achieve its full potent...

    Authors: Robert L. Davidson, Ralf J. M. Weber, Haoyu Liu, Archana Sharma-Oates and Mark R. Viant

    Citation: GigaScience 2016 5:10

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  13. Content type: TECHNICAL NOTE

    With next-generation sequencing (NGS) technologies, the life sciences face a deluge of raw data. Classical analysis processes for such data often begin with an assembly step, needing large amounts of computing...

    Authors: Yvan Le Bras, Olivier Collin, Cyril Monjeaud, Vincent Lacroix, Éric Rivals, Claire Lemaitre, Vincent Miele, Gustavo Sacomoto, Camille Marchet, Bastien Cazaux, Amal Zine El Aabidine, Leena Salmela, Susete Alves-Carvalho, Alexan Andrieux, Raluca Uricaru and Pierre Peterlongo

    Citation: GigaScience 2016 5:9

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  14. Content type: Data Note

    The cell line BT-474 is a popular cell line for studying the biology of cancer and developing novel drugs. However, there is no complete, published genome sequence for this highly utilized scientific resource....

    Authors: Serban Ciotlos, Qing Mao, Rebecca Yu Zhang, Zhenyu Li, Robert Chin, Natali Gulbahce, Sophie Jia Liu, Radoje Drmanac and Brock A. Peters

    Citation: GigaScience 2016 5:8

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  15. Content type: Research

    The miniaturised and portable DNA sequencer MinION™ has been released to the scientific community within the framework of an early access programme to evaluate its application for a wide variety of genetic app...

    Authors: Alfonso Benítez-Páez, Kevin J. Portune and Yolanda Sanz

    Citation: GigaScience 2016 5:4

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  16. Content type: Data Note

    Black shank is a severe plant disease caused by the soil-borne pathogen Phytophthora nicotianae. Two physiological races of P. nicotianae, races 0 and 1, are predominantly observed in cultivated tobacco fields ar...

    Authors: Hui Liu, Xiao Ma, Haiqin Yu, Dunhuang Fang, Yongping Li, Xiao Wang, Wen Wang, Yang Dong and Bingguang Xiao

    Citation: GigaScience 2016 5:3

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  17. Content type: Data Note

    The plant bug Lygus hesperus Knight is a polyphagous pest of many economically important crops. Despite its pest status, little is known about the molecular mechanisms responsible for much of the biology of this ...

    Authors: Erica E. Tassone, Scott M. Geib, Brian Hall, Jeffrey A. Fabrick, Colin S. Brent and J. Joe Hull

    Citation: GigaScience 2016 5:6

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  18. Content type: Data Note

    The Chinese mitten crab, Eriocheir sinensis, is one of the most studied and economically important crustaceans in China. Its transition from a swimming to a crawling method of movement during early development, a...

    Authors: Linsheng Song, Chao Bian, Yongju Luo, Lingling Wang, Xinxin You, Jia Li, Ying Qiu, Xingyu Ma, Zhifei Zhu, Liang Ma, Zhaogen Wang, Ying Lei, Jun Qiang, Hongxia Li, Juhua Yu, Alex Wong…

    Citation: GigaScience 2016 5:5

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  19. Content type: Research

    Resolution of complex repeat structures and rearrangements in the assembly and analysis of large eukaryotic genomes is often aided by a combination of high-throughput sequencing and genome-mapping technologies...

    Authors: Davide Verzotto, Audrey S. M. Teo, Axel M. Hillmer and Niranjan Nagarajan

    Citation: GigaScience 2016 5:2

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  20. Content type: Research

    Esophageal squamous cell carcinoma (ESCC) is the sixth most lethal cancer worldwide and the fourth most lethal cancer in China. Genomic characterization of tumors, particularly those of different stages, is li...

    Authors: Caixia Cheng, Heyang Cui, Ling Zhang, Zhiwu Jia, Bin Song, Fang Wang, Yaoping Li, Jing Liu, Pengzhou Kong, Ruyi Shi, Yanghui Bi, Bin Yang, Juan Wang, Zhenxiang Zhao, Yanyan Zhang, Xiaoling Hu…

    Citation: GigaScience 2016 5:1

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  21. Content type: Data Note

    Next-generation sequencing (NGS) technologies have changed our understanding of the variability of the human genome. However, the identification of genome structural variations based on NGS approaches with rea...

    Authors: Audrey S. M. Teo, Davide Verzotto, Fei Yao, Niranjan Nagarajan and Axel M. Hillmer

    Citation: GigaScience 2015 4:65

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  22. Content type: Technical Note

    Comprehensive recognition of genomic variation in one individual is important for understanding disease and developing personalized medication and treatment. Many tools based on DNA re-sequencing exist for ide...

    Authors: Siyang Liu, Shujia Huang, Junhua Rao, Weijian Ye, Anders Krogh and Jun Wang

    Citation: GigaScience 2015 4:64

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