Table 4 Time-line of resistance gene detection from the K. pneumoniae samples
Time | genes | Class | TP/FP | Sensitivity | Specificity | Data |
|---|---|---|---|---|---|---|
(mins) | (%) | (%) | (no. of reads) | |||
K. pneumoniae ATCC BAA-2146 | ||||||
30 | 1228 | |||||
mphA | macrolide | TP | ||||
blaSHV | beta-lactamase | FP ∗ | ||||
strA | aminoglycoside | TP | ||||
blaTEM | beta-lactamase | TP | ||||
strB | aminoglycoside | TP | ||||
blaCTX | beta-lactamase | TP | 26.67 | 87.50 | ||
60 | 2613 | |||||
blaLEN | beta-lactamase | TP | ||||
sul2 | sulphonamide | TP | ||||
blaOXA | beta-lactamase | TP | ||||
aac3 | aminoglycoside | TP | ||||
aac6 | aminoglycoside | TP | ||||
blaCMY | beta-lactamase | TP | ||||
blaCFE | beta-lactamase | TP | ||||
blaLAT | beta-lactamase | TP | ||||
blaBIL | beta-lactamase | TP | 53.33 | 94.12 | ||
90 | 3844 | |||||
QnrB | quinolone | TP | ||||
aadA | aminoglycoside | TP | ||||
oqxA | quinolone | TP | ||||
tetA | tetracycline | TP | ||||
oqxB | quinolone | TP | 76.67 | 95.83 | ||
120 | 5258 | |||||
dfrA | trimethoprim | TP | 80.00 | 96.00 | ||
240 | 10 788 | |||||
blaOKP | beta-lactamase | TP | 83.33 | 96.15 | ||
270 | 11 931 | |||||
rmtC | aminoglycoside | TP | 86.67 | 96.43 | ||
300 | 13 022 | |||||
sul1 | sulphonamide | TP | ||||
sul3 | sulphonamide | TP | 93.33 | 96.55 | ||
540 | 20 200 | |||||
fosA | fosfomycin | TP | 96.67 | 96.67 | ||
600 | 21 546 | |||||
blaNDM | beta-lactamase | TP | 100.00 | 96.77 | ||
K. quasipneumoniae ATCC 700603 | ||||||
30 | 582 | |||||
oqxA | quinolone | TP | ||||
blaSHV | beta-lactamase | TP | ||||
oqxB | quinolone | TP | 27.27 | 100.00 | ||
60 | 1090 | |||||
aadB | aminoglycoside | TP | 36.36 | 100.00 | ||
390 | 3704 | |||||
sul1 | sulphonamide | TP | ||||
sul3 | sulphonamide | TP | 54.55 | 100.00 | ||
420 | 3810 | |||||
blaOXA | beta-lactamase | TP | 63.64 | 100.00 | ||
540 | 4156 | |||||
blaOKP | beta-lactamase | TP | 72.73 | 100.00 | ||
K. pneumoniae ATCC 13883 | ||||||
30 | 1264 | |||||
fosA | fosfomycin | TP | 16.67 | 100.00 | ||
60 | 2186 | |||||
blaSHV | beta-lactamase | TP | ||||
blaOKP | beta-lactamase | TP | 50.00 | 100.00 | ||
90 | 2952 | |||||
blaLEN | beta-lactamase | TP | 66.67 | 100.00 | ||
120 | 3584 | |||||
oqxA | quinolone | TP | 83.33 | 100.00 | ||
570 | 8112 | |||||
oqxB | quinolone | TP | 100.00 | 100.00 | ||