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Table 3 Translocations confirmed by published RNA sequencing data

From: Whole genome sequence analysis of BT-474 using complete Genomics’ standard and long fragment read technologies

ChrA

GeneA

ChrA start

ChrA end

GeneA strand

ChrB

GeneB

ChrB start

ChrB end

GeneB strand

Paper

Supported by SV data

Supported by raw reads

1

AHCTF1

247,002,400

247,094,726

-

4

NAAA

76,831,808

76,862,166

-

Kangaspeska et al.

yes SV_ID37

yes

17

STARD3

37,793,333

37,820,454

+

20

DOK5

53,092,266

53,267,710

+

Edgren et al.

no

yes

20

VAPB

56,964,175

57,026,157

+

17

IKZF3

37,913,968

38,020,441

-

Edgren et al.

yes SV_ID124

yes

20

TRPC4AP

33,590,207

33,680,618

-

17

MRPL45

36,452,989

36,479,101

+

Kangaspeska et al.

no

yes

20

RAB22A

56,884,771

56,942,563

+

19

MYO9B

17,186,591

17,324,104

+

Edgren et al.

yes SV_ID145

yes

  1. Translocations identified in the standard and LFR libraries were compared to RNA sequencing identification of translocations in BT-474 from publications of Edgren et al. [7] and Kangaspeska et al. [8]. An explanation of the fields are as follows: chrA, the chromosome for the A side of the translocation; geneA, the gene affected on the A side of the translocation; chrA start, the start of the breakpoint region for the chrA side; chrA end, the end of the breakpoint region for the chrA side; geneA strand, the coding direction of the gene on the A side of the translocation; chrB, the chromosome for the B side of the translocation; geneB, the gene affected on the B side of the translocation; chrB start, the start of the breakpoint region for the chrB side; chrB end, the end of the breakpoint region for the chrB side; geneB strand, the coding direction of the gene on the B side of the translocation; paper, the publication in which the translocation was identified; supported by SV data (if there is evidence from at least one of our libraries to support this translocation a “yes” will appear in the table followed by the SV ID for our translocation, otherwise a “no” will appear); supported by raw reads (if there is evidence from at least one mate-pair read in one of our libraries to support this translocation a “yes” will appear in the table followed by the SV ID for our translocation, otherwise a “no” will appear)