Fig. 4

Circos plot of the BT-474 genome. Chromosome number (in large bold numbers and letters), chromosome position (in small numbers), and a karyotype ideogram form the outer circle of the plot. The remaining circles are described in order of outermost to innermost: called ploidy (the copy number of region; blue-gray), Lesser Allele Fraction (LAF, the fraction of the lesser allele, 0.5 for a heterozygous SNP, 0 for a homozygous SNP; green), density of heterzogous SNPs (orange), and density of homozygous SNPs (blue). Lines in the center of the plot represent interchromosomal junctions