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Table 5 Comparison of methods for overlap map-to-sequence alignment

From: OPTIMA: sensitive and accurate whole-genome alignment of error-prone genomic maps by combinatorial indexing and technology-agnostic statistical analysis

Algorithm Drosophila (A) Drosophila (B) Human (A) Human (B) Human real data
  E P E P E P E P E
OPTIMA-overlap 91 100 53 98 72 99 29 97 23
Gentig v.2 (d) 69 100 29 93 51 93 19 83 14
Likelihood-overlap (d + a) 59 74 36 52 21 41 9 26 12
  1. The precision of overlap alignments (P, in percentages) and the number of overlap alignments that lead to (correct) extensions (E, absolute values) as a measure of sensitivity (correctness is only known for simulated datasets) are shown. The best values across methods are highlighted in bold