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Fig. 4 | GigaScience

Fig. 4

From: Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma

Fig. 4

A view of the genome landscape of ESCCs at various stages. a Stage-distributions of candidate driver mutations identified by MutSigCV significance analysis. The type of each mutation is shown for every sample, including the gene-specific total number of mutated samples (right); mutation subtypes are denoted by color. If multiple mutations were found in a gene in a single sample, only one is shown. The significance of the mutations in each gene is shown to the left by the false discovery rate (FDR) q value. The lower bars indicate smoking/drinking status and family history, respectively. The full list of mutated genes is given in Additional file 8: Table S4. b Percentage of ESCC patients harboring one or two SMGs in the 104 cohort. The ESCC patients harboring none of the identified SMGs are also shown

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