Fig. 1
From: Single-molecule optical genome mapping of a human HapMap and a colorectal cancer cell line
Representative optical map of GM12878. DNA molecules were stretched and immobilized onto a glass MapCard surface with the aid of a channel-forming device, cut by KpnI, stained, and visualized by fluorescence imaging. Interrupted linear stretches indicate DNA digested by KpnI. Whirly, non-linear, short, and disjointed DNA molecules are filtered out by the image processing software