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Table 1 BRCA screening by ethnicity

From: Addressing health disparities in Hispanic breast cancer: accurate and inexpensive sequencing of BRCA1 and BRCA2

  West Eur Cent Eur Latin Am African Asian Nat Am Mid East All
BRCA1 2501 336 185 180 75 44 30 3351
BRCA2 1899 214 105 100 75 35 16 2444
Total mutant 4400 550 290 280 150 79 46 5795
Subjects 36235 4066 1936 1767 1183 597 492 46276
% Mutation 12 % 14 % 15 % 16 % 13 % 13 % 9 % 13 %
Ratio BRCA1/2 1.32 1.57 1.76 1.80 1.00 1.26 1.88 1.37
% Sample 78 % 9 % 4 % 4 % 3 % 1 % 1 %  
US pop (1000s) 196817   50477 37686 14465 2247   
Screened/100,000 18.4   3.84 4.69 8.18    
Ratio West Eur/minority   4.80 3.93 2.25    
  1. Data from Hall et al. [17] on BRCA screening and mutations identified by ethnic group were used to calculate the ratio of BRCA1/BRCA2 mutations (ratio BRCA1/2), and the percentage of the total sample represented by that ethnicity (% sample). The size of selected ethnic groups according to the US Census in thousands (US Pop (1000s)) divided by the number of subjects yields the number screened per 100,000 (Screened/100,000). The ratio of Western Europeans (West Eur) screened to Latin Americans (Latin Am), African Americans (African), and Asian American (Asians) was calculated by dividing Screened/100,000 for West Eur (18.4) by the corresponding figure of the minority population (Ratio West Eur/minority). Including the Central European (Cent Eur) women in with the West Eur women raises the minority ratios slightly (not shown)