Table 4 Enriched pathways in most predictive secondary community metabolome model features
From: Metabolome of human gut microbiome is predictive of host dysbiosis
KEGG ID | Pathway | Secondary metabolites | p-val |
|---|---|---|---|
map01061 | Biosynthesis of phenylpropanoids | L-Tryptophan | p-Coumaroyl-CoA | Coniferyl_alcohol | 4-Coumarate | Caffeate | Ferulate | Coniferyl_aldehyde | 4-Hydroxycinnamyl_aldehyde | 5-Hydroxyferulate | 5-Hydroxyconiferaldehyde | 7.93×10−7 |
map01120 | Microbial metabolism in diverse environments | 5-Phospho-alpha-D-ribose_1-diphosphate | 2,3-Dihydroxybenzoate | S-Benzoate_coenzyme_A | 2-Maleylacetate | 2,4-Dichlorophenol | 5,10-Methenyltetrahydromethanopterin | 5,10-Methylenetetrahydromethanopterin | 2-Dehydro-3-deoxy-6-phospho-D-gluconate | cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide | Aerobactin | Ectoine | 2-Chloromaleylacetate | 2-Hydroxy-cis-hex-2,4-dienoate | 4-Fluoromuconolactone | 2-Chloro-5-methylmaleylacetate | 1.57×10−2 |
map00940 | Phenylpropanoid biosynthesis | p-Coumaroyl-CoA | Coniferyl_alcohol | 4-Coumarate | Caffeate | Ferulate | Coniferyl_aldehyde | 4-Hydroxycinnamyl_aldehyde | 5-Hydroxyferulate | 5-Hydroxyconiferaldehyde | 5-Hydroxyconiferyl_alcohol | N1,N5,N10-Tri-_hydroxyferuloyl_-spermidine | 1.47×10−6 |
map04974 | Protein digestion and absorption | L-Tryptophan | L-Leucine | Tyramine | 1.26×10−2 |