Table 3 Enriched pathways in most predictive total community metabolome model features
From: Metabolome of human gut microbiome is predictive of host dysbiosis
KEGG ID | Pathway | Metabolites | p-val |
|---|---|---|---|
map00770 | Pantothenate and CoA biosynthesis | CoA | Pantetheine_4′-phosphate | Apo-_acyl-carrier-protein_ | 2.86×10−4 |
map00561 | Glycerolipid metabolism | Phosphatidate | Diglucosyl-diacylglycerol | Glycerophosphoglycoglycerolipid | 5.16×10−4 |
map00030 | Pentose phosphate pathway | 5-Phospho-alpha-D-ribose_1-diphosphate | D-Ribose_1,5-bisphosphate | 2-Dehydro-3-deoxy-6-phospho-D-gluconate | 6.71×10−4 |
map00361 | Chlorocyclohexane and chlorobenzene degradation | 2-Maleylacetate | 2,4-Dichlorophenol | cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide | 2-Chloromaleylacetate | 2.57×10−3 |
map00240 | Pyrimidine metabolism | | 5-Phospho-alpha-D-ribose_1-diphosphate | Thymine | 4.72×10−3 |
map00362 | Benzoate degradation | 2,3-Dihydroxybenzoate | S-Benzoate_coenzyme_A | 2-Maleylacetate | 6.56×10−3 |
map00627 | Aminobenzoate degradation | 2,3-Dihydroxybenzoate | S-Benzoate_coenzyme_A | 2-Maleylacetate | 6.56×10−3 |
map01120 | Microbial metabolism in diverse environments | 5-Phospho-alpha-D-ribose_1-diphosphate | 2,3-Dihydroxybenzoate | S-Benzoate_coenzyme_A | 2-Maleylacetate | 2,4-Dichlorophenol | 5,10-Methenyltetrahydromethanopterin | 5,10-Methylenetetrahydromethanopterin | 2-Dehydro-3-deoxy-6-phospho-D-gluconate | cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide | Aerobactin | Ectoine | 2-Chloromaleylacetate | 2-Hydroxy-cis-hex-2,4-dienoate | 4-Fluoromuconolactone | 2-Chloro-5-methylmaleylacetate | 1.57×10−2 |