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Table 6 Examples of predictions by CONS and individual-component methods. ATP-dependent RNA helicase SrmB (UniProt ID: P21507)

From: The PFP and ESG protein function prediction methods in 2014: effect of database updates and ensemble approaches

Method

GO id

Confidence score

GO term

CONS

GO:0005524

1.00

ATP binding

 

GO:0003676

0.29

nucleic acid binding

 

GO:0004386

0.24

helicase activity

 

GO:0000166

0.24

nucleotide binding

 

GO:0008026

0.24

ATP-dependent helicase activity

 

GO:0016787

0.20

hydrolase activity

 

GO:0003723

0.19

RNA binding

 

(GO:0003677)

0.17

 
 

…and 37 more terms

 
 

GO:0004004

0.04

ATP-dependent RNA helicase activity

 

GO:0044424

0.04

intracellular part

 

(GO:0051716)

0.04

 
 

(GO:0071843)

0.04

 
 

…and 142 more terms

 
 

GO:0000027

0.01

ribosomal large subunit assembly

 

(GO:0050789)

0.01

 
 

(GO:0051252)

0.01

 
 

…and 3 more terms

 
 

GO:0033592

0.01

RNA strand annealing activity

 

GO:0030687

0.01

preribosome, large subunit precursor

PFP

GO:0044464

1.00

cell part

 

GO:0008150

1.00

biological process

 

GO:0005623

1.00

cell

 

GO:0003676

1.00

nucleic acid binding

 

GO:0004386

0.99

helicase activity

 

GO:0005575

0.94

cellular component

 

GO:0022613

0.84

ribonucleoprotein complex biogenesis

 

GO:0003674

0.84

molecular function

 

(GO:0090304)

0.77

 
 

GO:0032559

0.76

adenyl ribonucleotide binding

 

GO:0005524

0.76

ATP binding

 

…and 116 more terms

 
 

GO:0004004

0.11

ATP-dependent RNA helicase activity

 

(GO:0080090)

0.10

 
 

(GO:0070013)

0.10

 
 

…and 407 more terms

 

ESG

GO:0000027

0.01

ribosomal large subunit assembly

 

GO:0000166

0.80

nucleotide binding

 

GO:0003676

0.80

nucleic acid binding

 

GO:0003723

0.80

RNA binding

 

GO:0005524

0.80

ATP binding

 

GO:0004386

0.73

helicase activity

 

GO:0008026

0.73

ATP-dependent helicase activity

 

GO:0016787

0.73

hydrolase activity

 

(GO:0000184)

0.46

 
 

(GO:0005634)

0.46

 
 

(GO:0006364)

0.46

 
 

GO 0042254

0.46

ribosome biogenesis

 

(GO:0005737)

0.38

 
 

GO:0004004

0.28

ATP-dependent RNA helicase activity

 

GO:0000027

0.07

ribosomal large subunit assembly

 

(GO:0005515)

0.07

 
 

GO:0030687

0.07

preribosome, large subunit precursor

 

GO:0033592

0.07

RNA strand annealing activity

  1. GO terms in bold are correct annotations of the protein. Terms in italic indicate parental terms of correct GO terms. Terms in parentheses are wrong predictions
  2. For CONS prediction, GO terms that have a confidence score equal to or larger than 0.0073 (i.e. up to the last correct GO term) are listed. For PFP prediction, GO terms that have a confidence score equal to or larger than 0.07 are listed. For ESG, all predicted GO terms are shown
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