Table 1 Samples analysed in this study and sequencing metrics

SOLiD v3

JWL(1ug)-E

82,825,332

25,878,330

31.24%

JWL(5ug)-E

41,496,636

16,004,583

38.57%

CEM-CCRF-E

70,843,054

23,576,689

33.28%

K562-E

67,818,656

19,407,273

28.62%

Leuk316-E

86,478,570

29,043,378

33.58%

Lap316-E

74,223,311

19,719,258

26.57%

Rem316-E

77,702,366

23,783,043

30.61%

NB-Leuk

84,461,471

44,789,628

53.03%

SOLiD v4

bm9_cd19-E

38,269,892

22,810,020

59.60%

bm9_cd19-I

37,784,067

34,877,526

92.31%

bm9_cd33-E

10,416,743

6,266,457

60.16%

bm9_cd33-I

42,759,158

39,428,521

92.21%

bm9_cd34-E

51,318,758

29,465,956

57.42%

bm9_cd34-I

46,036,938

42,428,715

92.16%

bm9_cd45-E

12,914,609

9,361,359

72.49%

bm9_cd45-I

33,483,409

31,189,190

93.15%

bm10_cd19-E

45,846,788

23,820,768

51.96%

bm10_cd19-I

42,916,292

39,433,442

91.88%

bm10_cd33-E

18,881,635

12,678,559

67.15%

bm10_cd33-I

36,392,688

33,622,173

92.39%

bm10_cd34-E

1,455,904

976,835

67.09%

bm10_cd34-I

43,740,869

38,954,344

89.06%

bm10_cd45-E

47,832,605

31,267,133

65.37%

bm10_cd45-I

56,272,359

51,839,725

92.12%

Lap197-E

23,613,069

17,771,922

75.26%

Lap197-I

40,839,842

37,160,823

90.99%

Lap316-E

22,312,029

18,406,671

82.50%

Lap316-I

65,985,869

59,587,559

90.30%

Lap362-E

26,103,269

18,291,098

70.07%

Lap362-I

43,663,529

39,464,174

90.38%

Lap367-E

30,436,848

22,390,188

73.56%

Lap367-I

61,426,571

55,393,215

90.18%

Leu135-E

28,518,319

22,184,998

77.79%

Leu135-I

66,384,953

59,496,167

89.62%

Leu197-E

40,781,905

21,042,700

51.60%

Leu197-I

100,952,576

88,986,493

88.15%

Leu292-E

37,383,290

27,245,488

72.88%

Leu292-I

81,946,813

73,469,308

89.65%

Leu316-E

19,691,035

15,476,011

78.59%

Leu316-I

49,443,957

44,399,793

89.80%

Leu362-E

26,155,137

19,508,962

74.59%

Leu362-I

52,718,699

47,588,023

90.27%

Leu367-E

30,436,848

22,390,188

73.56%

Leu367-I

61,426,571

55,393,215

90.18%

Leu378-E

37,963,480

25,159,304

66.27%

Leu378-I

63,946,621

57,452,718

89.84%

Leu386-E

34,541,207

26,730,838

77.39%

Leu386-I

85,783,795

76,829,088

89.56%

pbsc1_cd19-E

28,300,798

17,236,825

60.91%

pbsc1_cd19-I

42,994,203

39,873,845

92.74%

pbsc1_cd33-E

28,441,237

17,222,149

60.55%

pbsc1_cd33-I

41,190,719

38,084,036

92.46%

pbsc1_cd34-E

30,595,326

18,228,854

59.58%

pbsc1_cd34-I

40,582,296

37,607,618

92.67%

pbsc1_cd45-E

21,807,673

11,901,508

54.57%

pbsc1_cd45-I

44,739,461

41,071,013

91.80%

pbsc2_cd19-E

35,937,656

20,893,976

58.14%

pbsc2_cd19-I

39,678,926

36,769,939

92.67%

pbsc2_cd33-E

35,344,009

22,387,891

63.34%

pbsc2_cd33-I

32,507,100

30,204,900

92.92%

pbsc2_cd34-E

25,845,401

13,736,296

53.15%

pbsc2_cd34-I

48,706,315

44,827,413

92.04%

pbsc2_cd45-E

32,212,432

21,627,452

67.14%

pbsc2_cd45-I

47,235,290

43,581,366

92.26%

Rem135-E

36,998,278

24,794,225

67.01%

Rem135-I

123,775,359

108,611,090

87.75%

Rem197-E

32,669,979

20,692,190

63.34%

Rem197-I

72,248,569

64,234,959

88.91%

Rem292-E

40,308,561

29,524,878

73.25%

Rem292-I

56,187,553

50,646,668

90.14%

Rem316-E

29,052,098

23,634,221

81.35%

Rem316-I

60,566,396

54,693,711

90.30%

Rem362-E

30,583,568

24,759,911

80.96%

Rem362-I

59,138,768

53,532,111

90.52%

Rem367-E

27,854,950

20,285,938

72.83%

Rem367-I

53,616,042

48,017,388

89.56%

Rem378-E

19,428,372

14,820,513

76.28%

Rem378-I

58,333,370

51,624,942

88.50%

Rem386-E

26,909,681

19,355,786

71.93%

Rem386-I

83,504,227

74,547,836

89.27%

Total

3,671,922,955

2,741,473,297

74.66%