Figure 1From: Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smearsVenn diagrams summarising peak region overlaps between samples analysed in this study. Overlapping peak regions are shown after MACS peak analysis. (A) Peaks on chromosome 21 from three non-leukaemic individuals where CD19 cells were positively selected using FACS. A high degree of overlapping peaks were observed. (B) Peaks from matching leukaemic and remission samples from individual 135. Although there are some overlapping peaks (183), there are a substantial number of distinct peaks in each sample. (C) The extent of overlapping peaks between 3 leukaemic samples. (D) The extent of overlapping peaks between 3 remission samples.Back to article page