Figure 2

Use of the signed KS test on real data. The best HOMER [6] scores of the two motifs are computed for enhancers of the blood lineage and the active enhancers are compared with inactive enhancers in two cell types. (A) Comparison of Spi1 motifs in enhancers active in B cells versus inactive enhancers. The curves are shifted relative to each other, which means that the scores are lower overall in the active enhancers. (B) Comparison of the NRF1 motifs in the enhancers active in dendritic cells versus inactive enhancers. The curves cross each other, which means that the scores are more variable in active enhancers. However, the medians are very close.