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Table 5 –blocks runtimes (sec)

From: Second-generation PLINK: rising to the challenge of larger and richer datasets

Parameters

Dataset

Machine

Haploview 4.2

PLINK 1.07

PLINK 1.90

–ld-window-kb 500

synth1

Mac-2

nomem

3198.4

1.7

  

Mac-12

45 k

3873.0

1.3

  

Linux32-2

nomem

5441.1

3.4

  

Linux64-512

57 k

2323.4

2.9

  

Win32-2

nomem

9803.4

8.9

  

Win64-2

51 k

5513.4

2.8

–ld-window-kb 1000

synth1

Mac-2

nomem

6185.7

2.2

  

Mac-12

45 k

7394.4

9.8

  

Linux32-2

nomem

9876.8

10.0

  

Linux64-512

57 k

4462.1

3.9

  

Win32-2

nomem

18925.7

17.3

  

Win64-2

51 k

10.3 k

3.6

–ld-window-kb 500

chr1

Mac-2

nomem

2700 k?

550.9

  

Mac-12

nomem

3600 k?

426.0

  

Linux32-2

nomem

4300 k?

1288.4

  

Linux64-512

440 k?

2600 k?

1119.7

  

Win32-2

nomem

17000 k?

4535.8

  

Win64-2

nomem

5700 k?

1037.2

  1. This command breaks the genome into estimated “haplotype blocks” which are usually inherited together. The PLINK 1.9 implementation combines optimizations recently developed by Taliun et al. [26] with additional laziness and bit-level parallelism.