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Table 4 –indep-pairwise runtimes (sec)

From: Second-generation PLINK: rising to the challenge of larger and richer datasets

Parameters

Dataset

Machine

PLINK 1.07

PLINK 1.90

Ratio

50 5 0.5

synth1

Mac-2

701.3

0.63

1.1 k

  

Mac-12

569.4

0.55

1.0 k

  

Linux32-8

572.7

0.95

600

  

Linux64-512

462

0.60

770

  

Win32-2

1163.9

3.2

360

  

Win64-2

1091.9

1.0

1.1 k

700 70 0.7

synth2

Mac-2

120 k

31.9

3.8 k

  

Mac-12

63.0 k

20.6

3.06 k

  

Linux32-8

57.4 k

66.0

870

  

Linux64-512

120 k

26.4

4.5 k

  

Win32-2

139.3 k

127.3

1.09 k

  

Win64-2

200 k

22.9

8.7 k

20000 2000 0.5

chr1

Mac-2

nomem

1520.1

 
  

Mac-12

nomem

1121.7

 
  

Linux32-8

nomem

4273.9

 
  

Linux64-512

950 k

1553.3

610

  

Win32-2

nomem

4912.7

 
  

Win64-2

nomem

1205.1

 
 

1000g

Mac-2

nomem

20.5 k

 
  

Mac-12

nomem

14.5 k

 
  

Linux32-8

nomem

54.5 k

 
  

Linux64-512

13000 k

20.2 k

640

  

Win32-2

nomem

64.5 k

 
  

Win64-2

nomem

14.7 k

 
  1. This command is used to select a set of genetic markers which are not too highly correlated with one another. The PLINK 1.9 implementation benefits from laziness (i.e. the correlation coefficient between a pair of variants is no longer computed when it is not needed by the main pruning algorithm) and bitwise operations.