From: Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing
Clinical data | Couples | Total | |||
---|---|---|---|---|---|
Robertsonian translocation | Reciprocal translocation | Inversion | AMA and/or RM | ||
No. of couples treated | 58 | 144 | 11 | 53 | 266 |
Maternal age (years) | 30.6 | 30.4 | 31.8 | 35.1 | 31.4 |
No. of blastocysts biopsied | 229 | 606 | 47 | 176 | 1,058 |
Euploid (%) | 120 (52.4%) | 216 (35.6%) | 26 (55.3%) | 106 (60.2%) | 468 (44.2%) |
Numerical aberrations | 72 (31.4%) | 67 (11.1%) | 8 (17.0%) | 42 (23.9%) | 189 (17.9%) |
Imbalanced aberrations | 22 (9.6%) | 247 (40.8%) | 8 (17.0%) | 21 (11.9%) | 298 (28.2%) |
Numerical + imbalanced | 15 (6.6%) | 76 (12.5%) | 5 (10.7%) | 7 (4.0%) | 103 (9.7%) |