Table 4 The top 10 interactions that are predicted to be of high impact
PPI information | Publication information | |||||
|---|---|---|---|---|---|---|
Rank by impact | Gene symbols | Protein A name | Protein B name | Pubmed ID | Number of citations so far | Year of publication |
1 | ADIPOQ - ADIPOR2 | adiponectin, C1Q and collagen domain containing | adiponectin receptor 2 | 12802337 | 160 | 2003 |
2 | NMB - NMBR | neuromedin B | neuromedin B receptor | 8392057 | 8 | 1993 |
3 | NUP93 - TMEM48 | nucleoporin 93 k Da | transmembrane protein 48 | 12928435 | 37 | 2006 |
4 | DAO - DAOA | D-amino-acid oxidase | D-amino acid oxidase activator | 12364586 | 72 | 2002 |
5 | PCM1 - TIC8 | pericentriolar material 1 | tetratricopeptide repeat domain 8 | 14520415 | 99 | 2003 |
6 | PCM1 - KIAA0368 | pericentriolar material 1 | KIAA0368 | 16189514 | 413 | 2005 |
7 | BBS4 - PCM1 | Bardet-Biedl syndrome 4 | pericentriolar material 1 | 15107855 | 55 | 2004 |
8 | SRC - YWHAG | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 8702721 | 21 | 1996 |
9 | GRB2 - SRC | growth factor receptor-bound protein 2 | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 11964172 | 2 | 2002 |
10 | HCN2 - HCN4 | hyperpolarization activated cyclic nucleotide-gated potassium channel 2 | hyperpolarization activated cyclic nucleotide-gated potassium channel 4 | 12928435 | 26 | 2003 |