Figure 1From: Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer Somatic mutant allele frequency spectrum (SMAFS) of synonymous (green) and nonsynonymous (missense and nonsense, red) mutants. (A) Normal cell populations and (B) tumor cell populations. The allele frequency was binned to 10 columns; the first column denotes a frequency range from 0% to 10%, the second from 10% to 20%, and so forth.Back to article page